A confident and settled England side named their team on Monday.
England will play a Six Nations match without lock Maro Itoje on the pitch for the first time in seven years after the captain was named on the bench.
Itoje has been ever-present for England in the tournament since the start of 2020, playing all 80 minutes in 30 successive matches.
The British and Irish Lions lock missed the start of England’s preparations for the tournament in Girona to attend the funeral of his mother Florence in Nigeria.
Northampton duo Fraser Dingwall and Tommy Freeman have won the race to start at centres, while Bath wing Henry Arundell makes his first start since the 2023 World Cup.
Wales will wait until the more traditional Thursday slot to unveil Tandy’s first Six Nations squad.
England: Freddie Steward; Immanuel Feyi-Waboso, Tommy Freeman, Fraser Dingwall, Henry Arundell; George Ford, Alex Mitchell; Ellis Genge, Jamie George (capt), Joe Heyes, Alex Coles, Ollie Chessum, Guy Pepper, Sam Underhill, Ben Earl.
Replacements: Luke Cowan-Dickie, Bevan Rodd, Trevor Davison, Maro Itoje, Tom Curry, Henry Pollock, Ben Spencer, Marcus Smith.
Wales: tbc
Replacements: tbc
