While the Oregon Ducks enjoyed a well-earned bye in Week 6 after five straight wins to kick off the season, college football decided to have its wildest week yet.
Both Penn State and Texas (No. 6 and 7 in the Week 6 coaches poll) fell in surprising fashion. The Nittany Lions, who’s national title odds took a hit a week prior after their loss to the Ducks, were taken down by the previously 0-4 UCLA Bruins. Nico Iamaleava — who appeared in the College Football Playoff with the Tennessee Volunteers last season — looked like his old self in leading the upset win.
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Meanwhile, the Longhorns were defeated by Florida, preserving head coach Billy Napier’s job for one more week. Once again, Texas quarterback Arch Manning looked out of sorts, unable to live up to the sky high expectations placed upon him.
Elsewhere, Alabama won convincingly against previously undefeated Vanderbilt and placed themselves back in the national title conversation. Miami, thanks to the play of quarterback Carson Beck, went into Florida State and dominated the Seminoles, raising their national title odds as well.
Let’s take a look at the entire national title odds picture (per FanDuel Sportsbook) after the conclusion of Week 6.
Ohio State Buckeyes (+420)
Ohio State Buckeyes running back James Peoples (20) runs past Minnesota Golden Gophers defensive back Koi Perich (3) during the NCAA football game at Ohio Stadium in Columbus on Oct. 4, 2025. Ohio State won 42-3.
Previous Odds: +500
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Week 6 Result: W 42-3 vs. Minnesota
Record: 5-0, 2-0 Big Ten
Oregon Ducks (+550)
Sep 27, 2025; University Park, Pennsylvania, USA; Oregon Ducks running back Jordon Davison (0) reacts after scoring a touchdown against the Penn State Nittany Lions at Beaver Stadium. Mandatory Credit: Matthew O’Haren-Imagn Images
Previous Odds: +600
Week 6 Result: Bye
Record: 5-0, 2-0 Big Ten
Sep 27, 2025; Athens, Georgia, USA; Alabama Crimson Tide offensive lineman Kadyn Proctor (74) celebrates with quarterback Ty Simpson (15) after defeating the Georgia Bulldogs at Sanford Stadium. Mandatory Credit: Brett Davis-Imagn Images
Previous Odds: +800
Week 6 Result: W 30-14 vs. Vanderbilt
Record: 4-1, 2-0 SEC
Miami Hurricanes (+900)
Sep 20, 2025; Miami Gardens, Florida, USA; Miami Hurricanes running back CharMar Brown (6) carries the football against the Florida Gators during the fourth quarter at Hard Rock Stadium. Mandatory Credit: Sam Navarro-Imagn Images
Previous Odds: +1400
Week 6 Result: W 28-22 vs. Florida State
Record: 5-0, 1-0 ACC
Georgia Bulldogs (+1000)
Georgia quarterback Gunner Stockton (14) runs into the end zone for a touchdown during a college football game between Tennessee and Georgia at Neyland Stadium in Knoxville, Tenn., on Sept. 13, 2025.
Previous Odds: +950
Week 6 Result: W 35-14 vs. Kentucky
Record: 4-1, 2-1 SEC
Oklahoma Sooners (+1600)
Oklahoma Sooners wide receiver Isaiah Sategna III (5) scores a touchdown during a college football game between the University of Oklahoma Sooners (OU) and the Auburn Tigers at Gaylord Family à Oklahoma Memorial Stadium in Norman, Okla., Saturday,Sept. 20, 2025. Oklahoma won 24-17.
Previous Odds: +1900
Week 6 Result: W 44-0 vs. Kent State
Record: 5-0, 1-0 SEC
Texas A&M Aggies (+1600)
Sep 13, 2025; South Bend, Indiana, USA; Texas A&M Aggies quarterback Marcel Reed (10) looks to make a pass during the first half against the Notre Dame Fighting Irish at Notre Dame Stadium. Mandatory Credit: Michael Caterina-Imagn Images
Previous Odds: +2200
Week 6 Result: W 31-9 vs. Mississippi State
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Record: 5-0, 2-0 SEC
Texas Longhorns (+1800)
Texas quarterback Arch Manning (16) is tackled by San Jose State after keeping the ball for yardage during the first half at Darrell K Royal-Texas Memorial Stadium.
Previous Odds: +700
Week 6 Result: L 29-21 vs. Florida
Record: 3-2, 0-1 SEC
Ole Miss Rebels (+1900)
Ole Miss linebacker TJ Dottery (6) celebrates during a college football game between Ole Miss and LSU at Vaught-Hemingway Stadium in Oxford, Miss., on Saturday, Sept. 27, 2025. Ole Miss defeated LSU 24-19.
Previous Odds: +2000
Week 6 Result: Bye
Record: 5-0, 3-0 SEC
Aug 31, 2025; Miami Gardens, Florida, USA; Notre Dame Fighting Irish quarterback CJ Carr (13) drops back to pass against the Miami Hurricanes during the first quarter at Hard Rock Stadium. Mandatory Credit: Sam Navarro-Imagn Images
Previous Odds: +3500
Week 6 Result: W 28-7 vs. Boise State
Record: 3-2
Sep 12, 2025; Bloomington, Indiana, USA; Indiana Hoosiers defensive lineman Dominique Ratcliff (91) and Indiana Hoosiers defensive lineman Mario Landino (97) celebrate after a sack during the second half against the Indiana State Sycamores at Memorial Stadium. Mandatory Credit: Robert Goddin-Imagn Images
Previous Odds: +3500
Week 6 Result: Bye
Record: 5-0, 2-0 Big Ten
LSU wide receiver Chris Hilton Jr. (3) catches the ball during a college football game between Ole Miss and LSU at Vaught-Hemingway Stadium in Oxford, Miss., on Saturday, Sept. 27, 2025. Ole Miss defeated LSU 24-19.
Previous Odds: +3000
Week 6 Result: Bye
Record: 4-1, 1-1 SEC
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This article originally appeared on Ducks Wire: Where Oregon Ducks land in national title betting odds after Week 6
