Scotland make two changes to their starting XV, with Gregor Brown replacing Jonny Gray in the second row and Matt Fagerson in at number eight for Jack Dempsey, who is ruled out with a hamstring injury.
Lock Marshall Sykes, back-rower Ben Muncaster and versatile back Jamie Dobie come into the squad as replacements, with the former two set to make their Six Nations debuts.
Scotland: 15-Kinghorn; 14-Graham, 13-Jones, 12-Jordan, 11-Van der Merwe; 10-Russell (co-capt), 9-White; 1-Schoeman, 2-Cherry, 3-Z Fagerson, 4-Brown, 5-Gilchrist, 6-Ritchie, 7-Darge (co-capt), 8-M Fagerson.
Replacements: 16-Ashman, 17-Sutherland, 18-Hurd, 19-Gray, 20-Sykes, 21-Muncaster, 22-Dobie, 23-McDowall.
